Endocrine Abstracts

Insulin resistance, lipid imbalance and inflammatory process have deleterious effect on cardiovascular system. Omega-3 polyunsaturated fatty acids (n-3 PUFA) (Docosahexaenoic acid [DHA] and Eicosapentaenoic acid [EPA]) are lipids that have beneficial effects. Our objective was to study the effects of n-3PUFA on anthropometric characteristics, inflammation, lipid profile and insulin resistance of the children with obesity.Materials and methods: Thirty obe...

Obesity is one of the major causes of morbidity and mortality worldwide and is considered a risk factor for metabolic syndrome, type 2 diabetes and cardiovascular disease (CVD). miRNAs are epigenetic regulators of several aspects of metabolism and energy homeostasis and are involved in obesity and regulation of insulin sensitivity. miR 26b is among the obesity-related micoRNAs and is differentially expressed in preadipocytes and mature adipocytes in humans and is upregulated d...